A study published in Nature Metabolism shows that a specific class of drugs that block mitochondrial function can reverse ...

As expected, studies in mice and rats show that those following a Western diet tend to gain more weight than those eating standard chow 6,7, although the extent of the difference between ... Further ...

Blocking ABHD6 not only increased activity but also protected the mice from diet-induced obesity. The nucleus accumbens is a region of the brain known for its role in processing reward ...

High-fat diet (HFD) leads to obesity and metabolic syndromes and affects the functions in reproductive system. HFD-induced gut microbiota dysbiosis and endotoxaemia have ... at least some of these ...

The authors use this protocol to explore the cellular landscape in both lean and diet-induced obese mice, identifying a dysfunctional hypertrophic adipocyte subpopulation linked to obesity. The data ...