Australian researchers have successfully introduced an improved version of Cas12a gene-editing enzyme in mice.

Genetic changes are a significant cause of infertility, impacting over 15% of the global population. TLE6, a major protein ...

It’s a new way to create “bi-paternal” mice that can survive to adulthood—but human applications are still a long way off.

A research group led by Wei Li at the Chinese Academy of Sciences has created mice born from two male parents and capable of ...

Researchers say study represents a resource that could also help to dissect Y-gene functions in other tissues.

This is a useful study that seeks to address the role of the TET family of DNA demethylation enzymes in pancreatic beta cell senescence in the context of type 2 diabetes (T2DM). Although the concepts ...

New study reveals that TLE6 protein deficiency causes male infertility in mice. These findings suggest potential genetic ...

Gould and his colleague William Dove generated a rat knockout of the colon cancer–associated gene encoding adenomatous polyposis coli protein (Apc). Whereas mouse Apc knockouts mostly develop ...

Scientists have revealed the secret to the structural integrity of tiny particles that transport cargo from cell to cell through blood vessels and bodily fluids: special proteins that keep their ...

As primary spermatocytes of double knockout mice stop their differentiation in pachytene, we compared gene expression in two groups of germ cells: undifferentiated spermatogonia and meiosis-entry ...

Scientists uncover how Ffar4 regulates sugar cravings through gut microbiota, revealing pantothenate as a key mediator to curb sugar intake.