Each nutrient-specific pile was then linked to unique histone acetyltransferases, which are proteins that reshape DNA and influence which genes are expressed to change cellular behavior and identity.
The other fusion partners involved are CBP and TIF2, both of which are known transcriptional coactivators with intrinsic histone acetyltransferase activity. We have cloned MORF, a new human ...
KAT2A is a histone acetyltransferase that functions as a transcriptional activator which, together with its paralogue KAT2B, is markedly overexpressed in acute myeloid leukemia (AML) compared to in ...
1.*Ikeda, T., Uno, M., Honjoh, S. & Nishida, E.: "The MYST family histone acetyltransferase complex regulates stress resistance and longevity through transcriptional control of DAF-16/FOXO ...