1Cellular Degradation Biology Center, College of Medicine, Seoul National University, Seoul, Republic of Korea. 2Department of Biomedical Sciences, College of Medicine, Seoul National University, ...

Recent studies have identified that autophagy activation in oral epithelial cells suppresses cancer cell survival by inhibiting key pathways such as the mammalian target of rapamycin (mTOR) and ...

Autophagy counterbalances cellular stress associated with oncogenic KRAS activation, as do specific metabolic and reactive oxygen species detoxifying adaptions that represent acquired vulnerabilities.

demonstrated the implication of circ-TXNDC11 in MAPK/ERK pathway regulation, promoting RCC growth and invasion ... EMT activation, VEGF activation, apoptosis and autophagy, which are considered ...

Department of Biomedical Engineering, University of West Attica, Ag. Spyridonos, Egaleo 12243, Greece ...

The aim of this study was to investigate the mechanism of myocardial injury induced by aconitine. Using aconitine, ROS inhibitor N-acetylcysteine(NAC), the autophagy activitor Rapamycin (Rap) or the ...

Department of Microbiology and Immunology, College of Veterinary Medicine, Cornell University, Ithaca, USA Department of Microbiology, UMass Chan Medical School, , USA ...

microRNA-149-5p mediates the PM2.5-induced inflammatory response by targeting TAB2 via MAPK and NF-κB signaling pathways in vivo and in vitro. CaMKII and CaV3.2 T-type calcium channel mediate ...

ADAM17 indicates a disintegrin and metalloprotease 17; AT1R, angiotensin receptor type 1; Cav1, caveolin 1; ERK, extracellular signal–regulated kinase; HB-EGF, heparin-binding EGF-like growth factor; ...