Furthermore, the signaling metabolites succinate and itaconate can accumulate independently of characteristic breaks in the TCA cycle in mouse and human macrophages, and peritoneal macrophages can be ...

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Division of Physiological Chemistry and Metabolism, Faculty of Pharmacy, Keio University, 1-5-30 Shibakoen, Minato-ku, Tokyo 105-0011, Japan Laboratory of Metabolomics, RIKEN Center for Integrative ...

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In summary, nociceptors can utilize multiple neuropeptide-dependent and -independent means to exert control over macrophages, and, in vivo, the macrophage response will likely result from a ...

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Here, we study the effects of peritoneal Bacillus Calmette–Guérin (BCG ... Using lineage tracing, we find that tissue-resident red pulp macrophages (RPM), initially depleted by BCG exposure, are ...