Additionally, Mejias-Pena et al. found that compared to a sedentary group, elderly individuals showed significantly lower expression of NLRP3, caspase-1, and apoptosis-related genes (Bcl-2, Bcl-xL) in ...

The immunofluorescence without block of endogenous peroxidases was examined with incubation of primary anti-TH (1:500; Santa Cruz, sc-25269), anti-allograft inflammatory factor 1 (AIF1) (1:200; Abcam, ...

Both glucose deprivation and treatment with either 2-deoxyglucose or GLUT1 inhibitor suppressed crystal-induced NLRP3 activation and IL-1β production, and microcrystal inflammation in vivo. Conclusion ...