Background Piwi-interacting RNAs (piRNAs, 26-31 nucleotides) are recently described short regulatory RNAs, which build functional complexes with the four argonaute-subfamily members PIWI-like proteins ...

Piwi proteins are regulatory proteins whose major function is known in the maintenance of stem cells and differentiation with respect to germline cells. They are highly conserved RNA-binding proteins ...

This liquid biopsy contains various classes of RNA molecules, including messenger RNAs, microRNAs, piwi-interacting RNAs, transfer RNAs and other non-coding RNA (ncRNA) molecules. These circulating ...

The field of small RNA is one of the most investigated research areas since ... overlaps of reads on opposite strands to test ping-pong amplification for putative PIWI-interacting RNAs, providing ...

The Zamore laboratory studies Argonaute proteins and small RNA silencing pathways, including the RNA interference (RNAi), microRNA, and PIWI-interacting RNA pathways. Argonaute proteins are RNA- or ...