Sapio Sciences, the science-aware™ lab informatics platform, today announced that Schrödinger, a global leader in computational chemistry, has adopted the Sapio Platform to improve data management, ...

Here, the authors explore how composition and structure of protein aggregates affect dormancy and exit from this state. Outer membrane protein TraT protects bacteria from secondary F plasmid ...

This manuscript describes the identification and characterization of 12 specific phosphomimetic mutations in the recombinant full-length human tau protein that trigger tau to form fibrils. This ...

2018) and have significant nucleotide divergence across their backbones (Harmer and Hall, 2015) and, thus, IncA [reference plasmid pRA1 (Fricke et al., 2009)] and IncC should be separated from IncA/C ...

For example, many antibiotic-resistance genes spread through plasmid transfer between bacteria. However, bacteria also have numerous defense mechanisms aimed at eliminating any foreign DNA ...

The reactions were terminated at 95°C for 5 min, followed by the addition of 20 times the volume of methanol, and analysis by UPLC-MS. For structure confirmation, the sample was purified with semi ...

Capital structure is the mix of debt and equity that fund a company's operations. A judicious use of debt and equity is a key indicator of a strong balance sheet. A healthy capital structure that ...