The tiny protein known as transthyretin can cause big problems in the body when it misfolds after secretion. While healthy ...

These insights could drive the development of new drugs to treat transthyretin amyloidosis, a progressive and fatal disease.

Ramakrishnan, a distinguished structural biologist and Nobel Laureate in Chemistry (2009), is renowned for his groundbreaking ...

Monoclonal antibodies, or mAbs, are important tools in medicine. These laboratory-made proteins are widely used in treatments ...

Proteins, the pillars of cellular function, often assemble into "complexes" to fulfill their functions. A study by the ...

The human genome encodes potentially thousands of tiny proteins that were previously overlooked. The search is on to find out ...

The tiny protein known as transthyretin can cause big problems in the body when it misfolds after secretion. While healthy transthyretin moves hormones through blood and spinal fluid, misfolded ...

The protein was then synthesized and tested in the lab. It glowed—a clear sign of success. The AI had effectively charted a ...

Insights into the structures could lead to improved treatment strategies for transthyretin amyloidosis, a progressive, fatal disease in men.

Biomedical engineers at Duke University have developed an AI-based platform that designs short proteins, termed peptides, capable of binding and destroying previously undruggable disease-causing ...