This article examines viral and non-viral vectors in gene therapy, highlighting their mechanisms, advantages, and limitations ...

While there are RNAi products on the marketplace, with Alnylam becoming the first company to get a product approved in 2018, it is difficult to get this class of drug distributed through the brain ...

After hours: February 7 at 7:58:04 PM EST Loading Chart for RNA ...

【导读】结直肠癌（CRC）是全球最常见的癌症之一，肝转移是其致死的主要原因。环状 ...

Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. The endosomal pathway is essential for ...

2020年，詹妮弗·杜德纳（Jennifer A. Doudna）教授与埃马纽埃尔·夏彭蒂耶（Emmanuelle Charpentier）共同荣获诺贝尔化学奖，以表彰她们共同开发了基因组编辑方法CRISPR的卓越贡献。 受Frontiers for Young Minds邀请，杜德纳撰文解释了CRISPR的工作原理以及她与合作者是如何发现这一机制的。杜德纳说， ...

This can be done by providing a vector of paths to all the bam files you want to analyze together. The advantage of running samples together include: Novel transcripts that are identified in multiple ...

Qure is planning soon to start enrolling patients in a second dose group as part of a clinical trial testing AMT-162 for SOD1 ...

PARIS, France I February 12, 2025 I GenSight Biologics (Euronext: SIGHT, ISIN: FR0013183985, PEA-PME eligible), a biopharma company focused on developing and ...

Gene therapies to treat rheumatoid arthritis have evolved slowly, but one is ready to move into human trials and an ...

Here, the authors show that the unusual chromosome size-dependent DNA replication timing in Leishmania is influenced by RNA-DNA hybrids that are recognised by the endonuclease RNase H1.

Guided by RNA, the Cas9 endonuclease breaks DNA at a target sequence. Imprecise repair of the double strand break can result in insertion or deletion mutations, while repair pathways can be ...