Cytokine dysregulation is believed to play a key role in the remodeling of the immune system at older age, with evidence pointing to an inability to fine-control systemic inflammation, which seems to ...
Cytokines and their receptors play a major role in the pathogenesis and pathophysiology of human lymphomas. IL-13 is a growth factor for tumor cells in mycosis fungoides and Hodgkin lymphoma and is ...
Cytokines are proteins, peptides or glycoproteins secreted by lymphocytes and monocytes that regulate immune responses, haematopoiesis and lymphocyte development. Cytokines include interleukins ...
Mice with conditional knockout of Bmal1 in their disc cells demonstrated age-related degeneration of IVDs. Conclusions We have established autonomous circadian clocks in mouse and human IVD cells ...
The deal comes just a few days after Synthekine secured approval to start clinical trials in the US of its lead drug candidate STK-012, a partial agonist of the cytokine IL-2 that is being ...