knock-in models are developed by inserting a specific gene into a particular location within the genome. Various methods can ...

Transgenic and knockout mice have been used to create disease models and understand gene function. However, such mice are complex to create, breeding colonies must be established, and some models ...

Genetic changes are a significant cause of infertility, impacting over 15% of the global population. TLE6, a major protein involved in early embryonic development, is known to affect female fertility.