Stress affects the function of PD-L2-positive macrophages by disrupting the activity of the β2-adrenergic receptor (Adrb2). Macrophages that develop after the disruption of Adrb2 showed reduced ...

However, the study reveals that psychological stress affects their function by disrupting the activity of the β2-adrenergic receptor (Adrb2) activity. Macrophages that mature under this altered ...

Stress also leads to SNS release of norepinephrine acting on Adrb2 on monocytes and PD-L2 + macrophages. The reduction in efferocytosis-related gene expression causes dead cell accumulation in ...

Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. Pro-inflammatory macrophage activation is a ...