This study presents a valuable finding on the alterations in the autophagic-lysosomal pathway in a Huntington's disease model. The evidence supporting the claims of the authors is solid. However, the ...

The yeast cytoplasm-to-vacuole targeting (Cvt ... this structure is termed an autophagic body. The Cvt body is lysed and prApe1 is matured by proteolytic removal of a propeptide to generate ...

However, the physiological significance of autophagic degradation of the nucleus ... and is delivered to the vacuole. In contrast, in micronucleophagy, the nucleus's outer surface directly ...