This study presents a valuable finding on the alterations in the autophagic-lysosomal pathway in a Huntington's disease model. The evidence supporting the claims of the authors is solid. However, the ...

Henan Key Laboratory of Environmental and Animal Product Safety, College of Animal Science and Technology, Henan University of Science and Technology, Luoyang 471000, Henan,China ...

LCs were even present in the nose and ears of aged mice. Depending on the location, the stiffness and pliability of cartilage varies. The team wanted to understand how the lipid vacuoles inside LCs ...

MDC staining solution (Sigma) was dissolved in PBS. Adherent cells were incubated with MDC for 30 min at 37°C. After rinsing in washing buffer three times, MDC combined with acidic autophagic vesicles ...