Many bacteriophages can modulate host transcription. Here, the authors uncover the anti-termination mechanism of phage satellite P4 protein, Psu. Psu dimers clamp two open rings of the termination ...

For the multifaceted and complex diseases, multi-omics could define groups of patients with distinct endotypes exhibiting heterogeneous treatment responses due to their particular underlying molecular ...

Activating agents enable the efficient preparation of organozinc complexes from zinc metal and organohalides, but their mechanisms had been obscured by the heterogeneous nature of these systems.

From Drug Discovery Biology, Monash Institute of Pharmaceutical Sciences, Monash University, Parkville Campus, Victoria, Australia (R.H.R.) Division of Endocrinology and Metabolism (E.D.A.), ...

while sometimes an "abiding expression of faith," is also a culturally conditioned survival mechanism. For "people at the margins," she writes, extending "forgiveness" is sometimes a necessary ...

New research identifies key cellular mechanism driving Alzheimer's disease. ScienceDaily . Retrieved January 20, 2025 from www.sciencedaily.com / releases / 2024 / 12 / 241223135051.htm ...

Azvudine is under clinical development by Henan Genuine Biotech and currently in Phase II for Hepatocellular Carcinoma. According to GlobalData, Phase II drugs for Hepatocellular Carcinoma have a 33% ...

Azvudine is under clinical development by Henan Genuine Biotech and currently in Phase II for Lung Cancer. According to GlobalData, Phase II drugs for Lung Cancer have a 36% phase transition success ...

However, further research on the mechanisms of action, efficacy, and target populations of these novel therapeutic drugs are necessary. This study included mild, moderate, severe, and critical ...

School of Materials Science and Engineering, Key Laboratory of Automobile Materials of MOE, Electron Microscopy Center, Jilin University, Changchun 130012, China ...

While bumetanide effectively normalizes early social communication, its effects on post-pubertal social interaction suggest these behaviors may develop through different mechanisms or treatments ...

Employing gene-technological methods such as CRISPR-Cas9 genome editing, they were able to establish the molecular mechanisms of how mitochondria counteract cellular NAD decline. "Decreased ...