RAD54L2 deficiency phenocopies loss of BLM, including increases in sister chromatid exchanges and ultrafine anaphase bridges ... discovering statistically supported enrichments for DNA repair, DNA ...

The wide variety of congenital anomalies often accompanying constitutional aplastic anemia has led to its recognition as a distinctive syndrome. Congenital malformations have been the outstanding ...

We do not understand the nature of the factors that control the regional distribution of recombination along chromosomes, the mechanisms that control chromatid compaction and interference nor the ...

The targeting of telomeres offers promise for new cancer therapies, which can be aimed at disrupting the mechanisms that ...

A key target of the APC is securin, the destruction of which initiates chromosome segregation by unleashing the protease separase, which destroys sister-chromatid cohesion. The APC also ...

Researchers have uncovered which genes on the Y chromosome regulate the development of sperm and impact fertility in male mice. This research could help us understand why some men don't produce ...

Construction and iterative redesign of synXVI a 903 kb synthetic Saccharomyces cerevisiae chromosome. Nature Communications , 2025; 16 (1) DOI: 10.1038/s41467-024-55318-3 Cite This Page : ...

The battle against brain aging has a surprising new player: the X chromosome we inherit from our mothers. Recent research reveals that this genetic hand-me-down could influence how quickly our brains ...

Women are born with two X chromosomes and inherit one from each parent. But in every cell of their body, just one X chromosome is needed – so the other is randomly inactivated. Some cells use ...

Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. Chromosome segregation relies on kinetochores ...

College of Life Sciences, Fujian Provincial Key Laboratory of Haixia Applied Plant Systems Biology, State Key Laboratory of Ecological Pest Control for Fujian and Taiwan Crops, Haixia Institute of ...