other IDL particles are hydrolyzed in the liver by hepatic-triglyceride lipase to form LDL, a smaller, denser particle than IDL. LDL is the main carrier of circulating cholesterol within the body ...
Interconversion between lipid-free apolipoprotein AI, discoid lipid-poor pre-β-HDL, spherical small, dense HDL3, and large, light HDL2 mediated by lecithin:cholesterol acyltransferase ...
Hosted on MSN1mon
Promising therapeutic approach for metabolic liver diseases—researchers target enzyme related to fat metabolismA MedUni Vienna study has identified a new approach to the drug treatment of metabolic liver diseases ... III), focused on blocking ATGL (adipose triglyceride lipase). This enzyme plays a central ...
Hosted on MSN24d
Rare metabolic disorder can cause liver inflammationLysomal acid lipase (LAL) deficiency is a rare metabolic disorder that also causes liver inflammation ... such as cholesteryl esters and triglycerides, within the lysosomes, the "recycling ...
In FCS, mutations in the lipoprotein lipase gene lead to an accumulation of chylomicrons in plasma resulting in severe hypertriglyceridemia.
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