Promoter sequences are DNA sequences that define where transcription of a gene by RNA polymerase begins. Promoter sequences are typically located directly upstream or at the 5' end of the ...

DNA sequences that regulate expression of the insulin gene are located within a region spanning ~400 bp that flank the transcription start site. This region, the insulin promoter, contains a ...

On the other hand, invertebrate animals generally have a "mosaic" pattern of methylation, where regions of ... role in repressing gene expression, perhaps by blocking the promoters at which ...