gene knockout and knock-in studies are typically performed on cancer cell lines to investigate the efficacy of an existing ...

Australian researchers have successfully introduced an improved version of Cas12a gene-editing enzyme in mice.

Through a series of in vitro experiments ... the role of CDK4/CDK6 in ESCC was conducted through CRISPR-mediated gene knockout experiments. The depletion of CDK4/CDK6 in ESCC cells not only ...

To achieve their research goals, the lab employs a variety of experimental approaches, including in vivo models such as orthotopic xenograft models and patient-derived xenografts, as well as in vitro ...