Collectively, these studies indicate that ER stress is implicated in secondary brain injury after TBI and that targeting ER stress responses may be a mechanism to attenuate neuronal cell death and ...

Summary: Scientists have discovered that neural stem cells (NSCs) receive constant feedback from their daughter cells, influencing whether they remain dormant or activate to form new neurons and glia.

Following this, the secondary injury results in diffused cerebral damage in the peri-core area. However, the molecular mechanisms of neuronal death following an aneurysmal SAH are complex and ...

aol.com Background: Neuronal abnormalities are associated with the pathogenesis of diabetic retinopathy. However, the mechanisms for neuronal cell death in diabetic retinopathy remain unclear. Aim: To ...

Pancreas cells may produce a protein that can protect the brain from Alzheimer's disease. In individuals with Alzheimer's disease, a peptide known as amyloid-β accumulates and forms tangled plaques.

A new drug-free, minimally invasive intervention targets the root cause of progressive loss of neural function in spinal ...

NAIP5 (neuronal apoptosis inhibitory protein 5) mediates cell death in response to Legionella pneumophila, and NLRP1 mediates cell death in response to anthrax lethal toxin. In both cases ...

Multiple pathways of non-apoptotic cell death have recently been described, namely autophagic cell death, necroptosis and poly (ADP–ribose) polymerase-1 (PARP1)-mediated cell death. Emerging ...

A new UCLA Health study has discovered in mouse models that genes associated with repairing mismatched DNA are critical in ...

A new study has discovered in mouse models that genes associated with repairing mismatched DNA are critical in eliciting damages to neurons that are most vulnerable in Huntington's disease and ...

Conceptual diagram summarizing the central experiment comparing cell death in amyloid-β treated neuronal cells with and without pancreatic β cell culture supernatant. Pancreas cells may produce ...

A new electrical stimulation therapy for spinal muscle atrophy (SMA) has shown promise in reactivating motor neurons and ...