An in vivo base editing approach targeting the PRNP gene led to a 52% increase in the lifespan of mouse models inoculated with the most common sporadic and genetic types of human pathogenic prion ...

Gene therapy has emerged as a pivotal component in the treatment of diverse genetic and acquired human diseases. However, effective gene delivery remains a formidable challenge to overcome. The ...

Some genes are beneficial and enhance longevity. For example, the gene that helps a person metabolize cholesterol would reduce a person's risk of heart disease. Some gene mutations are inherited.

Gene regulation refers to the mechanisms that act to induce or repress the expression of a gene. These include structural and chemical changes to the genetic material, binding of proteins to ...

Each gene tells a cell to make a specific molecule, but this isn't performed by the DNA itself. Instead, the information is relayed to cellular machinery by a molecule called messenger RNA.

I was born on February 20, 1929, as Harry Eugene Rainbolt, son of Bertie and Clark Rainbolt, of Norman, Oklahoma, and the youngest of four children. All my life I was called Gene. Having an adoring, ...

New work by Columbia researchers has turned a textbook principle of genetics on its head and revealed why some people who carry disease-causing genes experience no symptoms. Every biology student ...

Diagram of the cellular copper metabolism pathway ... ATOX1 transfers copper to the nucleus, where it binds to transcription factors and drives gene expression. Additionally, ATOX1 facilitates copper ...

The specific questions taken up for study by the authors-in mice of HDAC and Polycomb function in the context of vascular endothelial cell (EC) gene expression relevant to the blood-brain barrier ...

BRMW is a free open source entity-relationship database modeling tool. We're working to make learning database modeling simple and accessible for everyone.

clang-uml is an automatic C++ to UML class, sequence, package and include diagram generator, driven by YAML configuration files. The main idea behind the project is to easily maintain up-to-date ...

including APOE. Its boundaries are not strictly defined, spanning a stretch between 0.2 and 10 Mb long. In 5’ to 3’ order, it usually includes the mitochondrial membrane translocase gene TOMM40, APOE, ...