Using glucocorticoids, rituzimab, or certain immunosuppressants to treat connective tissue diseases is associated with ...

Tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) induces apoptosis in various tumor cells in vitro, but its physiological role in tumor surveillance remains unknown. Here ...

Tumor necrosis factor receptor 1 (TNFR1) is a single-spanning type I transmembrane protein with several cysteine-rich extracellular domains, and also known as one of the major receptors of TNFα. Due ...

2Division of Cancer Immunology, Research Institute/Exploratory Oncology Research & Clinical Trial Center (EPOC), National Cancer Center, Tokyo, Japan. 6Department of Immunogenomic Medicine, Research ...

JAK inhibitors, a new class of tsDMARDs, have shown superior efficacy in RCTs for RA compared to other biologics. Real-world studies highlight JAK inhibitors' benefits in clinical disease activity ...

Background: To analyse available evidence on the efficacy and safety of anti-TNFα drugs (infliximab, etanercept and adalimumab) for treating rheumatoid arthritis (RA). Methods: We searched ...

Tumor necrosis factor (TNF) inhibitors led to no significant difference in survival or respiratory-related hospitalizations compared with non-TNF inhibitors, in patients with rheumatoid arthritis ...

Opens in a new tab or window Worries that tumor necrosis factor (TNF) inhibitors may exacerbate or even cause lung disease in patients with rheumatoid arthritis (RA) are unfounded, at least for U ...

Rheumatoid arthritis ... causing rashes are TNF inhibitors, hydroxychloroquine, and sulfasalazine, but any drug can be an offending agent,” he says. Tumor necrosis factor (TNF) is a protein ...