Tumour necrosis factor (TNF) inhibitors have changed the therapeutic standard of treatment for patients with rheumatoid arthritis (RA), providing substantial benefits in terms of clinical and ...

It may be concluded that the three marketed anti-TNFα drugs are more effective than the corresponding control treatments (MTX or placebo) in RA patients, with an NNT of 5 for ACR20 and ACR50 and ...

Treatment with TNF inhibitors yielded no differences in outcomes vs. other antirheumatic therapies among U.S. veterans with ...

Targeted drugs for rheumatoid ... inhibitors reported decreases in pain that were an average of 4.0 points greater (95% CI ...

Worries that tumor necrosis factor (TNF) inhibitors may exacerbate or even cause lung disease in patients with rheumatoid arthritis (RA) are unfounded, at least for U.S. military veterans ...

The effects of tumor necrosis factor inhibition on carcinogenesis ... this increased risk can be attributed to the use of cytokine inhibitors, to the underlying disease, or to other ...

A large European study finds that TNF inhibitors work differently across joints in psoriatic arthritis, with the shoulder and ...

Exposure to TNF inhibitors was linked to a reduced risk for cardiovascular events among patients with AS; the impact of IL-17 inhibitors was less clear.

Investigators used Veterans Administration data to assess the relationship among rheumatoid ... rheumatoid arthritis patients treated with triple therapy or tumor necrosis factor inhibitor.

Rheumatoid arthritis (RA ... Specifically, the efficacy of tumor necrosis factor (TNF) inhibitors was notably impacted by BMI, while other therapies like IL-23 and IL-17 inhibitors showed more ...

Using glucocorticoids, rituzimab, or certain immunosuppressants to treat connective tissue diseases is associated with greater risks for severe COVID-19-related outcomes.