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上海交大胥川团队提出并论证了mRNA m5C修饰的“分子错误”观点
CDS和3'-UTR) 的m 5 C修饰位点及其cis-elements都没有更高的保守性。5) 经过推测,超过80%的m 5 C修饰是非适应性的。这些发现表明mRNA m 5 C修饰大部分是非适应性的,主要应源自于修饰机器的错误运行,符合“分子错误”理论。此外,作者还提出和讨论了发掘适应性m 5 C ...
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