A knockout mouse, or knock-out mouse, is a genetically modified mouse (Mus musculus) in which researchers have inactivated, or "knocked out", an existing gene by replacing it or disrupting it …

The most common type is the knockout mouse, where the activity of a single (or in some cases multiple) genes are removed. They have been used to study and model obesity, heart disease, …

Accelerate your research with custom-engineered knockout (ko) mouse models. Design your own conditional and constitutive knockout mice or use existing strains.

2013年8月1日 · Everyone in biomedical research is familiar with "knockout" mice, animals that have had a particular gene silenced during their development. This can be a powerful way of …

2024年2月15日 · In 2006, the NIH initiated the Knockout Mouse Phenotyping Project (KOMP) with the goal of systematically knocking out every protein-coding gene in the mouse. Observing the …

The generation and analysis of genetically modified mice, including transgenic and knockout animals, is an essential technology for cancer research. The Genetically Modified Mouse …

knockout mouse, genetically engineered laboratory mouse (Mus musculus) in which a specific gene has been inactivated, or “knocked out,” by the introduction of a foreign (artificial) DNA …

The Knockout Mouse Project (KOMP) is providing critical tools for understanding gene function and the genetic causes of human diseases. Coordinated by the International Mouse …

2024年12月11日 · Kids First, Knockout Mouse Phenotyping Program (KOMP2) and the IMPC are collaborating on a pilot project to develop mouse strains to study, phenotype, and validate …

Generate custom designed conditional knockout mice with leading timelines using our revolutionary 3R-awarded goGermline™ technology.