Although this strain is refractory to many tumors, it is a permissive background for maximal expression of most mutations. C57BL/6J mice are resistant to audiogenic seizures, have a …

C57BL/6， 常被称作“C57 black 6”、“C57”或者“black 6”（标准简称为B6）, 是一种常见的近交品系实验鼠。 在遗传学试验中广泛用作转基因鼠以模拟人类的基因缺陷类疾病。

C57BL/6, often referred to as "C57 black 6", "B6", "C57" or "black 6", is a common inbred strain of laboratory mouse. It is the most widely used "genetic background" for genetically modified …

C57BL/6 ，“C57 black 6”、“C57”或者“black 6”（标准简称为B6），是 实验小鼠 常见的 近交品系。 人类疾病模型应用最广泛应用都基于C57BL/6转基因小鼠，其可用作同类系、易于繁殖并且 …

C57BL/6 ，「C57 black 6」、「C57」或者「black 6」（標準簡稱為B6），是 實驗小鼠 常見的 近交品系。 人類疾病模型應用最廣泛應用都基於C57BL/6轉基因小鼠，其可用作同類系、易於 …

免疫检查点人源化小鼠模型，通过将人源基因替换对应小鼠基因，使小鼠只表达人源的免疫检查点蛋白，从而成为药物评价的理想模型。 集萃药康 同时开发了基于BALB/c 和 C57BL/6两种背 …

Aged C57BL/6J mice have research applications that include immunology, cancer, longevity interventions, and biomarker studies. C57BL/6J is the most widely used inbred strain and the …

2017年10月2日 · Inbred mice are critical tools in biomedical research and one particular strain, known as C57BL/6 (Black 6 or B6, for short), is rapidly becoming the standard model for many …

As a popular subline, C57BL/6 is a productive inbred strain of lab mouse (Peters and Festing, 1985), with characteristics of stain stability, easy breeding, and short life span.

C57BL/6 substrains are not the same! Once a new C57BL/6 substrain is established, spontaneous mutations will arise in both the original colony, and the new colony. A subset of …