2024年2月21日 · Natural killer (NK) cells are lymphocytes of the innate immune system. A key feature of NK cells is their ability to recognize a wide range of cells in distress, particularly …

2024年5月15日 · CAR NK cell therapy bolsters the body’s innate ability to fight cancer by attaching molecules called chimeric antigen receptors (CAR) to natural killer cells (NK cells). …

Compared with other immunotherapies, NK cell therapy has its advantages. With their major histocompatibility complex (MHC)-antigen stimulating independent cytotoxicity, better safety, …

2021年8月17日 · This review describes the current status of NK cell therapy for cancer treatment based on the effector function and releasing the inhibited state of NK cells in the cancer …

2024年3月5日 · Natural killer (NK) cell-based immunotherapies are attracting increasing interest in the field of cancer treatment. Early clinical trials have shown promising outcomes, alongside …

In treatments of solid tumors, adoptive transfer of ex vivo expanded natural killer (NK) cells has dawned as a new paradigm. Compared with cytotoxic T lymphocytes, NK cells take a unique …

2022年5月23日 · As a promising alternative platform for cellular immunotherapy, natural killer cells (NK) have recently gained attention as an important type of innate immune regulatory …

2021年1月6日 · In this review, we provide our current understandings of NK cell biology, ongoing pre-clinical and clinical development of NK cell-based therapies and discuss the progress, …

2022年7月25日 · Strategies for the development of NK cell-based therapies focus on enhancing NK cell potency and persistence through co-stimulatory signalling, checkpoint inhibition and …

Natural killer cells may be used as immunotherapy during cancer treatment. Learn how NK cell therapy targets diseased cells and what the side effects are.