2023年4月29日 · Having at least one APOE e4 gene doubles or triples the risk of getting Alzheimer's disease. Some people have two APOE e4 genes, one from each parent. Having two genes increases the risk of getting Alzheimer's disease even more, about eight- to twelvefold.

2021年3月16日 · APOE4 is the strongest risk factor gene for Alzheimer’s disease, although inheriting APOE4 does not mean a person will definitely develop the disease. The study suggests that dementia may be caused by lipid imbalances in brain cells.

2024年8月21日 · The APOE gene test identifies the types of the APOE gene in your DNA. The APOE4 gene increases your risk of developing Alzheimer’s disease. The test results aren’t a diagnosis.

2024年6月7日 · The proposal poses a challenging question of whether to test people for the specific gene variant APOE4, which has long been linked to Alzheimer’s disease.

2023年4月12日 · Apolipoprotein E, commonly known as APOE, is a gene associated with varying risk of developing Alzheimer's disease, depending on which variant you have. There are three different variants—APOE2, APOE3, and APOE4—and you have two copies, one each from your mother and father.

One well-known gene that influences Alzheimer’s risk is the apolipoprotein E (APOE) gene. The APOE gene is involved in making a protein that helps carry cholesterol and other types of fat in the bloodstream. Problems in this process are thought to …

Researchers estimate that between 40-65% of people diagnosed with Alzheimer's have the APOE-e4 gene. APOE-e4 is one of three common forms of the APOE gene; the others are APOE-e2 and APOE-e3. We all inherit a copy of some form of APOE from each parent.

2024年9月12日 · Certain versions of the fibronectin 1 gene may protect people with the APOE ε4 gene from increased Alzheimer’s disease risk, according to an NIA-funded study.

Studies have long shown that if you carry two copies of the apolipoprotein E (APOE) 4 gene, your chances of developing Alzheimer’s disease are much higher. Now, researchers say in a new study...

Researchers found that the APOE4 gene may increase the risk of developing Alzheimer’s disease and other dementias by altering brain cells’ lipid metabolism. Choline supplements reversed these defects in cell studies, supporting further research in people carrying APOE4.