Leukotriene modifiers include two types of agents: Leukotriene synthesis inhibitors, such as zileuton, block the enzyme, 5-lipoxygenase, which is necessary for the formation of leukotrienes. Montelukast, zafirlukast, and zileuton may be considered for the treatment of asthma.

2021年6月2日 · Leukotriene modifiers, also called leukotriene receptor antagonists, are a group of medications. They can help prevent breathing problems associated with allergies, asthma and chronic obstructive pulmonary disease.

2024年2月20日 · Leukotriene modifiers work by blocking the action of leukotrienes, one cause of the inflammation and nasal congestion associated with allergies. For those with allergies and asthma,...

2023年8月10日 · Leukotriene modifiers help treat asthma symptoms by altering the action of leukotrienes, molecules that play a role in airway inflammation and constriction. Learn more.

2023年6月4日 · Bronchoconstriction, vascular permeability, eosinophil recruitment, and chronic inflammation are mediated through the G protein-coupled activation of cysteinyl leukotriene receptors. Montelukast and zafirlukast are antagonists to cysteinyl leukotriene CysLT1 receptors but not CysLT2 receptors.

2024年6月14日 · Leukotriene modifiers are used for the prevention and chronic treatment of asthma, exercise-induced bronchoconstriction (EIB), and seasonal allergic rhinitis. Learn more about types of leukotriene modifiers here.

An antileukotriene, also known as leukotriene modifier and leukotriene receptor antagonist, is a medication which functions as a leukotriene-related enzyme inhibitor (arachidonate 5-lipoxygenase) or leukotriene receptor antagonist (cysteinyl leukotriene receptors) and consequently opposes the function of these inflammatory mediators ...

There are two types of leukotriene modifier: leukotriene synthesis inhibitors and cysteinyl leukotriene receptor antagonists. 2 Both are used to block the bronchoconstrictor and pro-inflammatory activity of cysteinyl leukotrienes within the asthmatic airway.

1998年4月4日 · There are two types of leukotriene modifier: leukotriene synthesis inhibitors and cysteinyl leukotriene receptor antagonists. 2 Both are used to block the bronchoconstrictor and pro-inflammatory activity of cysteinyl leukotrienes within the asthmatic airway.

The leukotriene modifiers can be divided into two pharmacologic categories: the leukotriene receptor antagonists, zafirlukast (ACCOLATE®) and montelukast (SINGULAIR®), and the 5-lipoxygenase inhibitors, zileuton (ZYFLO®) and zileuton extended-release (ZYFLO CR®).