- Microglia are the main immunocompetent cells of the nervous system and their role in brain development and maintenance of proper neuronal function throughout life is widely recognized (1, 2).了解详细信息：Microglia are the main immunocompetent cells of the nervous system and their role in brain development and maintenance of proper neuronal function throughout life is widely recognized (1, 2).www.science.org/doi/10.1126/science.aax6752Microglia are innate immune cells of the central nervous system that sense extracellular cues.pubmed.ncbi.nlm.nih.gov/33369790/Microglia are resident cells of the brain that regulate brain development, maintenance of neuronal networks, and injury repair.pmc.ncbi.nlm.nih.gov/articles/PMC8167938/Microglia are a type of glial cell which are essential for the defense mechanisms in the central nervous system (CNS).www.kenhub.com/en/library/physiology/microglia
Microglia rescue neurons from aggregate-induced …
2024年7月25日 · Microglia are crucial for maintaining brain health and neuron function. Here, we report that microglia establish connections with neurons using tunneling nanotubes (TNTs) in both physiological and pathological conditions. …
Negative feedback control of neuronal activity by …
2020年9月30日 · Microglia, the brain’s resident macrophages, help to regulate brain function by removing dying neurons, pruning non-functional synapses, …
- 作者: Ana Badimon, Hayley J. Strasburger, Pinar Ayata, Xinhong Chen, Aditya Nair, Ako Ikegami, Ako Ikegami...
- Publish Year: 2020
Microglia monitor and protect neuronal function …
Mechanisms underlying microglia–neuron communication remain elusive. Here, we identified an interaction site between neuronal cell bodies and microglial processes in mouse and human brain. Somatic microglia–neuron junctions …
Microglia-neuron crosstalk: Signaling mechanism and control of
The alteration of neuron-microglia communication contributes to brain disease states with consequences, ranging from synaptic function to neuronal survival. This review focuses on the …
New Insights into Microglia-Neuron Interactions: A Neuron's
2019年5月1日 · Microglia are the primary immune cells of the central nervous system. However, recent data indicate that microglia also contribute to diverse physiological and …
Microglia-neuron crosstalk: Signaling mechanism and control of …
2019年10月1日 · The alteration of neuron-microglia communication contributes to brain disease states with consequences, ranging from synaptic function to neuronal survival. This review …
Current perspectives on microglia-neuron communication in the …
2024年12月1日 · Highlights • Microglia interact directly/indirectly with neurons, playing a crucial CNS role. • Microglia regulate key neuronal functions such as synaptic pruning and …
Microglia-neuron interaction at nodes of Ranvier depends on
2021年9月1日 · The mechanisms for microglia-neuron communication remain largely unkown. Here, we identify nodes of Ranvier as a direct site of interaction between microglia and axons, …
Microglia - Wikipedia
Microglia are a type of glial cell located throughout the brain and spinal cord of the central nervous system (CNS). [1] Microglia account for about 10–15% of cells found within the brain. [2] As the resident macrophage cells, they act as the …
Microglia in neurodegenerative diseases: mechanism and potential ...
2023年9月22日 · Here we comprehensively review the biology of microglia and the roles of microglia in neurodegenerative diseases, including Alzheimer’s disease, Parkinson’s disease, …
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