Pristane is a natural saturated terpenoid alkane obtained primarily from shark liver oil, from which its name is derived (Latin pristis, "shark"). It is also found in the stomach oil of birds in the order Procellariiformes and in mineral oil and some foods. [2]

Pristane is a natural or synthetic isoprenoid hydrocarbon (C19) derivative, Pristane is commonly used in research to prime the abdomen prior to hybridoma implantation in experimental animals. An irritant that induces granulomatous inflammation and interferes with local lymphatic drainage, it increases ascitic yields.

Pristane, also known as norphytane, is a saturated norterpenoid alkane derived from phytane. Its immunological properties are valuable for various applications, serving as an inflammation-inducing agent in tumorigenesis and autoimmune disease induction, facilitating research on conditions like rheumatoid arthritis and lupus.

Pristane is a branched alkane (2,6,10,14-tetramethylpentadecane), present in chlorophyll and normally occurring also in mammals, originating from food intake. From: Journal of Autoimmunity, 2003

Pristane is a pharmacologically induced model of SLE (Systemic Lupus Erythematosus) that is used to study the influence of environmental triggers on the development of this autoimmune disease. AI generated definition based on: International Review of Cell and Molecular Biology , …

2025年1月21日 · Pristane is a hydrocarbon oil adjuvant widely used to induce tumorigenesis in mice and arthritis and lupus nephritis in rats. It works as a adjuvant for monoclonal antibody generation in mouse ascites.

Pristane is a natural saturated terpenoid alkane obtained primarily from shark liver oil, from which its name is derived (Latin pristis, "shark"). It is also found in the stomach oil of birds in the order Procellariiformes and in mineral oil and some foods. [2]

We therefore investigated the role of OGG1 in the pristane-induced lupus (PIL) mouse model of IFN-driven SLE, which recapitulates numerous human SLE manifestations, including elevated type I IFNs, autoantibody generation, arthritis, and severe glomerulonephritis (17, 18).

Pristane Product Number P 1403 Store at Room Temperature Product Description Molecular Formula: C19H40 Molecular Weight: 268.5 CAS Number: 1921-70-6 Density: 0.782 g/ml Congealing Point: -100 °C1 2,6,10,14-Tetrametylpentadecane (Pristane) is used to precondition the peritoneal cavity of mice, prior to the

We investigated the protective role of chloroquine against pristane-induced macrophage activation, oxidative stress, and Th1/Th2 skewness in C57BL/6J mice. Those mice were treated with pristane alone or combined with chloroquine.