Schematic map of the human APOE gene.
ApoE plays many important roles in lipoprotein/ cholesterol metabolism, participates in lipid transport in CNS, and can indirectly regulate Aβ metabolism, as well as directly interact …
Apolipoprotein E - Wikipedia
The gene, APOE, is mapped to chromosome 19 in a cluster with the apolipoprotein C1 (APOC1) gene and the apolipoprotein C2 (APOC2) gene. The APOE gene consists of four exons and three introns, totaling 3597 base pairs.
The structure of APOE gene | Download Scientific …
APOE is a lipoprotein which functions in lipid transport, metabolism, and inflammatory modulation. Isoform specific effects of APOE within the brain include alterations to Aβ, tau ...
APOE Gene - GeneCards | APOE Protein | APOE Antibody
2024年12月24日 · The protein encoded by this gene is a major apoprotein of the chylomicron. It binds to a specific liver and peripheral cell receptor, and is essential for the normal catabolism of triglyceride-rich lipoprotein constituents. …
APOE ( 154 ) - ALZFORUM
Positions based on the mature protein, 299 amino acids long, appear in gray (diagram) and in parentheses (table). References for ApoE domains and regions can be found in Methods. Click on the amino acids in the diagram or on the …
APOE apolipoprotein E [Homo sapiens (human)] - Gene - NCBI
2025年1月4日 · This gene maps to chromosome 19 in a cluster with the related apolipoprotein C1 and C2 genes. Mutations in this gene result in familial dysbetalipoproteinemia, or type III …
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AceView: Gene:APOE, a comprehensive annotation of human, …
Apolipoprotein E, a main apoprotein of the chylomicron, binds to a specific receptor on liver cells and peripheral cells. ApoE is essential for the normal catabolism of triglyceride-rich lipoprotein …
Introducing Alzforum Database of 137 APOE Gene Variants
The table below the diagram lists the corresponding variants based on the selected filter. Clicking on a link for a specific variant, the user can then read a summary of the data reported for that …
A schematic of the APOE gene. Structure and …
The human apolipoprotein E (APOE) gene is polymorphic, with three primary alleles (E2, E3, E4) that differ at two key non-synonymous sites.