Many rat/mouse pressure ulcer (PU) models have been developed to test different hypotheses to gain deeper understanding of various causative risk factors, the progress of PUs, and assessing effectiveness of potential treatment modalities.

2010年5月1日 · Many rat/mouse pressure ulcer (PU) models have been developed to test different hypotheses to gain deeper understanding of various causative risk factors, the progress of PUs, and assessing effectiveness of potential treatment modalities.

Many rat/mouse pressure ulcer (PU) models have been developed to test different hypotheses to gain deeper understanding of various causative risk factors, the progress of PUs, and assessing effectiveness of potential treatment modalities.

Pressure ulcer (PU) can initiate in deep muscle closer to bony prominences. The recently emphasized deep tissue injury (DTI) mechanism has received increased attention and several studies reported newly developed DTI animal models. However, concerns exist for the clinical relevance and validity of these models.

The model rats develop a superficial PU‐like ulcer during the initial phase and develop a deep ulcer by PWD 11. We expect that this model will help clarify the mechanisms of DTI deterioration and allow for development of novel treatments to prevent DTI deterioration.

Many rat/mouse pressure ulcer (PU) models have been developed to test different hypotheses to gain deeper understanding of various causative risk factors, the progress of PUs, and assessing effectiveness of potential treatment modalities.

压疮 （pu） 是一个世界性的问题，由于相关的炎症反应、局部缺氧和反复缺血/再灌注，给患者带来巨大的痛苦和经济负担，因此难以解决。 中药龟板粉可治疗皮肤外伤，但其成分复杂，使用不便。

2024年2月14日 · Pressure ulcer (PU) is a worldwide problem that is difficult to address because of the related inflammatory response, local hypoxia, and repeated ischaemia/reperfusion, causing great suffering and financial burden to patients. Traditional Chinese medicine turtle plate powder can treat skin trauma, b …

2010年5月1日 · Many rat/mouse pressure ulcer (PU) models have been developed to test different hypotheses to gain deeper understanding of various causative risk factors, the progress of PUs, and assessing effectiveness of potential treatment modalities.

2015年10月1日 · In this study, we used Sprague-Dawley (SD) rats to generate a stage III PU model and transplanted human amniotic epithelial cells (hAECs) to treat stage III PU, aiming to evaluate its impacts on healing time and pathological conditions of PU and providing a basis for preclinical studies of hAECs in treating refractory stage III PU.